Copper(<scp>ii</scp>) curcumin complexes for endoplasmic reticulum targeted photocytotoxicity
Atrayee Banaspati, Vanitha Ramu, Md Kausar Raza, Tridib Kumar Goswami
Abstract
generation of cytotoxic reactive oxygen species upon photoactivation. Confocal microscopic images using complex 3 demonstrate localization of the complexes predominantly in the endoplasmic reticulum of HeLa cells.
Topics & Concepts
CurcuminHeLaChemistryEndoplasmic reticulumCytotoxicityApoptosisToxicityA549 cellPhotodynamic therapyCell biologyCancer researchBiochemistryBiologyCellIn vitroOrganic chemistryPhotodynamic Therapy Research StudiesPorphyrin and Phthalocyanine ChemistryCurcumin's Biomedical Applications