Activated Notch1 promotes macrophage polarization and exacerbates sepsis-induced acute lung injury via β-catenin/NF-κB signaling
Zhi Liu, Yuxi Lei, Jing Zuo, Ruiyu Zhang, Hui Du, Huizhi Hu, Junwen Zheng, Yang Pu, Dongchi Zhao
Topics & Concepts
NF-κBMacrophage polarizationSepsisSignal transductionMacrophageLungCancer researchCateninNFKB1MedicineChemistryCell biologyWnt signaling pathwayImmunologyInternal medicineBiologyIn vitroTranscription factorBiochemistryGeneNeonatal Respiratory Health ResearchMacrophage Migration Inhibitory FactorMicroRNA in disease regulation