A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms
Nazar Mashtalir, Hiroshi Suzuki, Daniel P. Farrell, Akshay Sankar, Jie Luo, Martin Filipovski, Andrew R. D’Avino, Roodolph St. Pierre, Alfredo M. Valencia, Takashi Onikubo, Robert G. Roeder, Yan Han, Yuan He, Jeffrey A. Ranish, Frank DiMaio, Thomas Walz, Cigall Kadoch
Topics & Concepts
SMARCA4NucleosomeBiologyChromatinProtein subunitSWI/SNFHomology modelingChromatin remodelingChromatin structure remodeling (RSC) complexCell biologyEndogenyHistoneBiophysicsComputational biologyGeneticsDNABiochemistryGeneEnzymeChromatin Remodeling and CancerGenomics and Chromatin DynamicsCancer Mechanisms and Therapy