Electrospun flexible magnesium-doped silica bioactive glass nanofiber membranes with anti-inflammatory and pro-angiogenic effects for infected wounds
Mingyue Liu, Xiangsheng Wang, Jie Cui, Hongsheng Wang, Binbin Sun, Jufang Zhang, Bernd Rolauffs, Muhammad Shafiq, Xiumei Mo, Zhanyong Zhu, Jinglei Wu
Abstract
in mice, it effectively inhibits bacterial infection. Both gene expression and histological/immunohistochemical analyses confirmed the down-regulated pro-inflammatory factors, up-regulated anti-inflammatory factors, and enhanced angiogenesis. Taken together, these desirable properties work in concert to contribute to the rapid healing of infected wounds and make it a good candidate for wound dressing materials.
Topics & Concepts
NanofiberMaterials scienceMembraneMagnesiumElectrospinningDopingChemical engineeringNanotechnologyComposite materialChemistryMetallurgyOptoelectronicsBiochemistryPolymerEngineeringBone Tissue Engineering MaterialsElectrospun Nanofibers in Biomedical ApplicationsWound Healing and Treatments