Nimbolide-encapsulated PLGA nanoparticles induces Mesenchymal-to-Epithelial Transition by dual inhibition of AKT and mTOR in pancreatic cancer stem cells
Deepika Singh, Priyanka Mohapatra, Sugandh Kumar, Somalisa Behera, Anshuman Dixit, Sanjeeb Kumar Sahoo
Topics & Concepts
PI3K/AKT/mTOR pathwayEpithelial–mesenchymal transitionPancreatic cancerProtein kinase BMesenchymal stem cellCancer stem cellCancer researchChemistryStem cellCell biologyBiologyCancerSignal transductionMedicineDownregulation and upregulationBiochemistryInternal medicineGeneCancer Cells and MetastasisMicrotubule and mitosis dynamicsPancreatic and Hepatic Oncology Research