A Central Role for Magnesium Homeostasis during Adaptation to Osmotic Stress
Brian M. Wendel, Hualiang Pi, Larissa Krüger, Christina Herzberg, Jörg Stülke, John D. Helmann
Abstract
Environments with high concentrations of salt or other solutes impose an osmotic stress on cells, ultimately limiting viability by dehydration of the cytosol. A very common cellular response to high osmolarity is to immediately import high levels of potassium ion (K + ), which helps prevent dehydration and allows time for the import or synthesis of biocompatible solutes that allow a resumption of growth.
Topics & Concepts
Osmotic shockHomeostasisOsmotic concentrationChemistryCytosolLimitingPotassiumOsmotic pressureMagnesiumDehydrationBiophysicsOsmosisBiocompatible materialBiochemistryCell biologyBiologyEnzymeMembraneMedicineGeneEngineeringBiomedical engineeringMechanical engineeringOrganic chemistryMagnesium in Health and DiseaseAluminum toxicity and tolerance in plants and animals