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Aseptic meningoencephalitis after COVID-19 vaccination: A case report

Shwan A. Ahmad, Bestoon Kh Salih, Karokh F. Hama Hussein, Tomas M. Mikael, Fahmi H. Kakamad, Abdulwahid M. Salih

2021Annals of Medicine and Surgery19 citationsDOIOpen Access PDF

Abstract

INTRODUCTION: Several types of vaccine have been shown to significantly reduce the risk of severe coronavirus disease 2019 (COVID-19). This study aims to report the first case of meningoencephalitis after receiving the second dose of Pfizer COVID-19 vaccine. CASE REPORT: A 62-year-old lady presented with headache, fever and rigor for 4 days. She had acute confessional state and inability to talk. She was conscious, disoriented, not obeying commands. Acyclovir vial IV 750 mg three times a day for 14 days were prescribed. She responded very well. DISCUSSION: Concern has been raised about the safety of vaccinations. The most common side effects of COVID-19 vaccinations are local responses at the injection site, followed by non-specific systemic symptoms such as headache, tiredness, myalgia, and fever. These may appear shortly after immunization and disappear in a short period of time CONCLUSION: Although extremely rare, aseptic meningoencephalitis could occur after COVID-19 vaccination. The patient could be managed conservatively with a good clinical outcome.

Topics & Concepts

MedicineMeningoencephalitisVaccinationmyalgiaAseptic meningitisPediatricsCoronavirus disease 2019 (COVID-19)Adverse effectSurgeryMeningitisAnesthesiaInternal medicineDiseaseImmunologyInfectious disease (medical specialty)Autoimmune Neurological Disorders and TreatmentsLong-Term Effects of COVID-19Pneumocystis jirovecii pneumonia detection and treatment
Aseptic meningoencephalitis after COVID-19 vaccination: A case report | Litcius