IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases
Yang Zhao, Jiangqing Chen, Massimo Andreatta, Bing Feng, Yuqing Xie, Mathias Wenes, Yi Wang, Min Gao, Xiaomeng Hu, Pedro Romero, Santiago J. Carmona, Jie Sun, Yugang Guo, Li Tang
Topics & Concepts
Chimeric antigen receptorTumor microenvironmentCancer researchMelanomaCancerT cellImmune systemImmunotherapyCancer cellImmunologyBiologyMedicineInternal medicineCAR-T cell therapy researchImmune Cell Function and InteractionT-cell and B-cell Immunology