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Granzyme K activates the entire complement cascade

C. Donado, Erin Theisen, Fan Zhang, Aparna Nathan, Madison L. Fairfield, Karishma Vijay Rupani, Dominique Jones, Kellsey Johannes, Accelerating Medicines Partnership RA/SLE Network, Jennifer S. Albrecht, Jennifer H. Anolik, William Apruzzese, Jennifer L. Barnas, Joan M. Bathon, Ami Ben‐Artzi, Brendan F. Boyce, David L. Boyle, S. Louis Bridges, Vivian P. Bykerk, Debbie Campbell, Arnold Ceponis, Adam Chicoine, Michelle Curtis, Kevin D. Deane, Edward F. DiCarlo, Laura T. Donlin, Patrick Dunn, Andrew Filer, Hayley Carr, Gary S. Firestein, Lindsy Forbess, Laura Geraldino‐Pardilla, Susan M. Goodman, Ellen M. Gravallese, Deepak A. Rao, Peter K. Gregersen, Joel M. Guthridge, María Gutiérrez‐Arcelus, V. Michael Holers, Diane Horowitz, Laura B. Hughes, Lionel B. Ivashkiv, Kazuyoshi Ishigaki, Judith A. James, Joyce B. Kang, Gregory Keras, Amit Lakhanpal, James A. Lederer, Myles Lewis, Yuhong Li, Katherine P. Liao, Arthur M. Mandelin, Ian Mantel, Kathryne E. Marks, Mark Maybury, Andrew McDavid, Mandy J. McGeachy, Joseph Mears, Nida Meednu, Nghia Millard, Larry W. Moreland, Saba Nayar, Alessandra Nerviani, Dana E. Orange, Harris Perlman, Costantino Pitzalis, Javier Rangel‐Moreno, Karim Raza, Yakir Reshef, Christopher T. Ritchlin, Felice Rivellese, William H. Robinson, Laurie Rumker, Ilfita Sahbudin, Saori Sakaue, Jennifer Seifert, Dagmar Scheel‐Toellner, Anvita Singaraju, Kamil Slowikowski, Melanie H. Smith, Darren Tabechian, Paul J. Utz, Kathryn Weinand, Dana Weisenfeld, Michael H. Weisman, Qian Xiao, Zhu Zhu, Zhihan J. Li, Andrew Cordle, Aaron Wyse, Soumya Raychaudhuri, Daniel F. Dwyer, A. Helena Jonsson, Michael B. Brenner

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Topics & Concepts

CascadeComplement (music)Granzyme BGranzymeGranzyme ACell biologyChemistryBiologyImmunologyBiochemistryImmune systemT cellCD8PerforinGenePhenotypeChromatographyComplementationComplement system in diseasesRenal Diseases and GlomerulopathiesApelin-related biomedical research