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The Characteristics, Mechanisms and Therapeutics: Exploring the Role of Gut Microbiota in Obesity

Zequn Zhuang, Peng Zhou, Jing Wang, Xiaojing Lu, Yigang Chen

2023Diabetes Metabolic Syndrome and Obesity32 citationsDOIOpen Access PDF

Abstract

Presently, obesity has emerged as a significant global public health concern due to its escalating prevalence and incidence rates. The gut microbiota, being a crucial environmental factor, has emerged as a key player in the etiology of obesity. Nevertheless, the intricate and specific interactions between obesity and gut microbiota, along with the underlying mechanisms, remain incompletely understood. This review comprehensively summarizes the gut microbiota characteristics in obesity, the mechanisms by which it induces obesity, and explores targeted therapies centered on gut microbiota restoration.

Topics & Concepts

Gut floraObesityBiologyEtiologyMechanism (biology)BioinformaticsMedicineImmunologyInternal medicineEndocrinologyPhilosophyEpistemologyGut microbiota and healthDiet and metabolism studiesDietary Effects on Health