Novel mycoplasma nucleomodulin MbovP475 decreased cell viability by regulating expression of CRYAB and MCF2L2
Gang Zhao, Doukun Lu, Shujuan Wang, Hui Zhang, Xifang Zhu, Zhiyu Hao, Ali Dawood, Yingyu Chen, Elise Schieck, Changmin Hu, Xi Chen, Liguo Yang, Aizhen Guo
Abstract
genes, and subsequently down-regulates their expression and decreases BoMac cell viability. Therefore, this study offers a new understanding of mycoplasma pathogenesis.
Topics & Concepts
BiologyElectrophoretic mobility shift assayVirulenceTranscription factorGeneCell biologyPromoterViability assayGeneticsDNA-binding domainGene expressionCellMolecular biologyMicrobial infections and disease researchAquaculture disease management and microbiotaBacteriophages and microbial interactions