Correlation of PD-L1 and SOCS3 Co-expression with the Prognosis of Hepatocellular Carcinoma Patients
Liuxi Chen, Xingxing Huang, Wenzheng Zhang, Ying Liu, Bi Chen, Xiang Yu, Ruonan Zhang, Mingming Zhang, Jiao Feng, Shuiping Liu, Ting Duan, Xiaying Chen, Wengang Wang, Ting Pan, Lili Yan, Ting Jin, Guohua Li, Yongqiang Li, Tian Xie, Xinbing Sui
Abstract
Purpose: To investigate the correlation between the expression of PD-L1, SOCS3 and immune-related biomarkers CD276, CD4, CD8 in hepatocellular carcinoma (HCC) and further determine the relationship with clinicopathologic characteristics and the prognostic value of their co-expression in HCC patients.
Topics & Concepts
Hepatocellular carcinomaMedicineImmunohistochemistryInternal medicineSOCS3CD8GastroenterologyPD-L1Proportional hazards modelOncologyCorrelationStage (stratigraphy)CirrhosisImmune systemCancer researchCancerImmunotherapyImmunologyBiologySuppressorGeometryMathematicsPaleontologyCancer Immunotherapy and BiomarkersHepatocellular Carcinoma Treatment and PrognosisImmunotherapy and Immune Responses