G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD
Alyssa N. Coyne, Benjamin L. Zaepfel, Lindsey R. Hayes, Boris Fitchman, Yuval Salzberg, En‐Ching Luo, Kelly Bowen, Hannah Trost, Stefan Aigner, Frank Rigo, G Yeo, Amnon Harel, Clive N. Svendsen, Dhruv Sareen, Jeffrey D. Rothstein
Topics & Concepts
NucleoporinC9orf72Nuclear poreCell biologyBiologyRanInduced pluripotent stem cellNuclear transportNeurodegenerationCell nucleusTrinucleotide repeat expansionNucleusGeneticsGenePathologyMedicineDiseaseEmbryonic stem cellAlleleAmyotrophic Lateral Sclerosis ResearchRNA Research and SplicingNeurogenetic and Muscular Disorders Research