Reisolation and Structure Revision of Asperspiropene A
Van Anh Cao, Byeoung-Kyu Choi, Hwa‐Sun Lee, Chang-Su Heo, Hee Jae Shin
Abstract
Asperspiropene A was originally reported to have a unique 1,8-dioxaspiro[4.5]decane skeleton. During the course of our ongoing research for novel marine natural products, we isolated compound 1, which has identical 1D and 2D NMR data to asperspiropene A. Detailed and careful analysis of spectroscopic data led us to revise the structure of asperspiropene A and to determine its absolute configuration.
Topics & Concepts
DecaneAbsolute configurationStereochemistrySkeleton (computer programming)Carbon skeletonChemistryComputer scienceOrganic chemistryProgramming languageMarine Sponges and Natural ProductsMicrobial Natural Products and BiosynthesisSeaweed-derived Bioactive Compounds