Synergy in Nanomedicine: What It Is Not, and What It Might Be
Steven J. Staffa, Daniel S. Kohane, David Zurakowski
Abstract
Interactions between nanoformulations delivering two or more drugs-or a drug and some other therapeutic modality-are often described as synergistic. In fact, synergy is a specific term of art, with important therapeutic implications. The term is often misused in the nanoscience literature. Here we discuss what synergy is and an approach to demonstrating it rigorously.
Topics & Concepts
NanomedicineTerm (time)NanotechnologyModality (human–computer interaction)Therapeutic modalitiesDrug deliveryComputer scienceMedicineManagement scienceEngineeringNanoparticleMaterials scienceHuman–computer interactionPhysicsPhysical therapyQuantum mechanicsNanoparticle-Based Drug DeliveryMolecular Communication and NanonetworksGold and Silver Nanoparticles Synthesis and Applications