Visible light-mediated ring opening and cyclization of aryl cyclopropanes: efficient synthesis of pyrrolo[1,2-<i>a</i>]quinoxalin-4(5<i>H</i>)-ones with antineoplastic activity
Jiabin Shen, Yong Yang, Chao Chen, Hao Xu, Chao Shen, Pengfei Zhang
Abstract
This study describes an efficient and green approach for the synthesis of potentially bioactive pyrrolo[1,2- a ]quinoxalin-4(5 H )-ones with appreciable functional group tolerance and a wide substrate scope.
Topics & Concepts
ChemistryArylRing (chemistry)Medicinal chemistryStereochemistryCombinatorial chemistryOrganic chemistryAlkylCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsSynthesis and Biological Evaluation