Low shear stress induced vascular endothelial cell pyroptosis by TET2/SDHB/ROS pathway
Jinna Chen, Jianwu Zhang, Jiaxiong Wu, Shulei Zhang, Yamin Liang, Bin Zhou, Peng Wu, Dangheng Wei
Topics & Concepts
PyroptosisSDHBReactive oxygen speciesChemistryCell biologyDownregulation and upregulationApoptosisProgrammed cell deathOxidative stressCancer researchSmall hairpin RNABiologyGene knockdownBiochemistryMutationGeneGermline mutationPeroxisome Proliferator-Activated ReceptorsInflammasome and immune disordersMitochondrial Function and Pathology