Expanding the scope of novel 1,2,3-triazole derivatives as new antiparasitic drug candidates
Renzo Carlucci, Gabriel Di Gresia, Marı́a G. Mediavilla, Julia A. Cricco, Babu L. Tekwani, Shabana I. Khan, Guillermo R. Labadié
Abstract
We have previously shown that prenyl and aliphatic 1,2,3-triazoles displayed antiparasitic and antimycobacterial activity. Herein, new series of analogues were prepared looking for antimalarial drug candidates.
Topics & Concepts
AntiparasiticAntimycobacterialDrugAntiparasitic agentScope (computer science)ChemistryTriazoleCombinatorial chemistryPharmacologyStereochemistryMedicineOrganic chemistryComputer scienceTuberculosisMycobacterium tuberculosisProgramming languagePathologyClick Chemistry and ApplicationsSynthesis and biological activityHIV/AIDS drug development and treatment