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Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus

Scott A. Jenks, Kevin S. Cashman, Esther Zumaquero, Urko M. Marigorta, Aakash V. Patel, Xiaoqian Wang, Deepak Tomar, Matthew C. Woodruff, Zoe Simon, Regina Bugrovsky, Emily L. Blalock, Christopher D. Scharer, Christopher M. Tipton, Chungwen Wei, Sei-Young Lim, Michelle Petri, Timothy B. Niewold, Jennifer H. Anolik, G. R. Gibson, F. Eun-Hyung Lee, Jeremy M. Boss, Frances E. Lund, Igñacio Sanz

2020Immunity52 citationsDOIOpen Access PDF

Topics & Concepts

EffectorImmunologyBiologySystemic lupus erythematosusAntibodyReceptorToll-Like Receptor 9Toll-like receptorConfusionTLR9AutoimmunityDiseaseImmune systemInnate immune systemGeneticsMedicineGenePathologyPsychoanalysisPsychologyGene expressionDNA methylationSystemic Lupus Erythematosus ResearchImmune Response and InflammationT-cell and B-cell Immunology