Case Report: Insulin-Dependent Diabetes Mellitus and Diabetic Keto-Acidosis in a Child With COVID-19
Karin Nielsen‐Saines, Erica Li, Adriana Martinez Olivera, Rachel Martin‐Blais, Yonca Bulut
Abstract
During the COVID pandemic, a surge in pediatric Type 1 Diabetes Mellitus (T1DM) cases appears to be occurring, potentially due to the presence of autoantibody-induced immune dysregulation triggered by COVID-19. We describe one such case in a previously healthy 7-year-old with asymptomatic COVID-19 presenting with a high nasopharyngeal SARS CoV-2 virus load, detectable COVID-19 IgG antibodies, diabetic keto-acidosis and islet cell autoantibodies. COVID-19 is not a trivial disease in children and adolescents and can lead to lifelong sequelae such as T1DM. Raising awareness about a possible association between COVID-19 and T1DM in children is critical.
Topics & Concepts
MedicineType 1 diabetesAsymptomaticAutoantibodyDiabetes mellitusCoronavirus disease 2019 (COVID-19)Diabetic ketoacidosisInsulinPandemicInternal medicineDiseaseImmunologyAntibodyEndocrinologyInfectious disease (medical specialty)Diabetes and associated disordersCOVID-19 Clinical Research StudiesDiabetes Management and Research