Efferocytosis drives a tryptophan metabolism pathway in macrophages to promote tissue resolution
Santosh R. Sukka, Patrick B. Ampomah, Lancia Darville, David Ngai, Xiaobo Wang, George Kuriakose, Yuling Xiao, Jinjun Shi, John M. Koomen, Robert H. McCusker, Ira Tabas
Topics & Concepts
EfferocytosisInflammationMacrophageCell biologyIndoleamine 2,3-dioxygenaseKynurenineKynurenine pathwayLipid signalingBiologyAryl hydrocarbon receptorLipid metabolismChemistryImmunologyBiochemistryTryptophanIn vitroAmino acidTranscription factorGenePhagocytosis and Immune RegulationTryptophan and brain disordersBirth, Development, and Health