Chromeno[3″,4″:5′,6′]pyrido[2′,3′:4,5]thieno[3,2-e]pyridine—A New Heterocyclic System. Synthesis andMolecular and Crystal Structures
I. V. Dyachenko, V. D. Dyachenko, Ilya A. Yakushev, Victor N. Khrustalev, В. Г. Ненайденко
Abstract
Multicomponent condensation of cyanothioacetamide, 4-fluoro-2-methylbenzaldehyde, methyl 4-methyl-3-oxopentanoate, and 3-(2-bromoacetyl)-2H-chromen-2-one afforded a new heterocyclic system, substituted chromeno[3″,4″:5′,6′]pyrido[2′,3′:4,5]thieno[3,2-e]pyridine. The molecular and crystal structures of the product were determined by X-ray analysis.
Topics & Concepts
ChemistryPyridineStereochemistryCombinatorial chemistryMedicinal chemistrySynthesis and biological activitySynthesis of Organic CompoundsSynthesis and Characterization of Heterocyclic Compounds