Genes with differential expression across ancestries are enriched in ancestry-specific disease effects likely due to gene-by-environment interactions
Juehan Wang, Zixuan Zhang, Zeyun Lu, Nicholas Mancuso, Steven Gazal
Topics & Concepts
Genome-wide association studyBiologyGeneGeneticsGenetic associationAlleleGenetic genealogyExpression quantitative trait lociComputational biologySingle-nucleotide polymorphismGenotypePopulationMedicineEnvironmental healthGenetic Associations and EpidemiologyEpigenetics and DNA MethylationRNA modifications and cancer