Structure and mechanism of the γ-secretase intramembrane protease complex
Michael S. Wolfe, Yinglong Miao
Topics & Concepts
PresenilinTransmembrane proteinTransmembrane domainAmyloid precursor protein secretaseLipid bilayerProteaseProteolysisAmyloid precursor proteinChemistryEnzymeBiophysicsBiochemistryBiologyMembraneReceptorAlzheimer's diseaseDiseasePathologyMedicineAlzheimer's disease research and treatmentsSupramolecular Self-Assembly in MaterialsPrion Diseases and Protein Misfolding