Phase I clinical trial of EGFR-specific CAR-T cells generated by the piggyBac transposon system in advanced relapsed/refractory non-small cell lung cancer patients
Yajun Zhang, Zhiwei Zhang, Yongmei Ding, Yuan Fang, Pei Wang, Wenqi Chu, Zhenlin Jin, Xintao Yang, Jiangtao Wang, Jinxing Lou, Qijun Qian
Topics & Concepts
Chimeric antigen receptorInternal medicineLung cancerMedicineHematologyEpidermal growth factor receptorCytokine release syndromeAdverse effectClinical trialImmunologyCancerOncologyGastroenterologyImmunotherapyCAR-T cell therapy researchCancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses