Litcius/Paper detail

The selective PPAR-delta agonist seladelpar reduces ethanol-induced liver disease by restoring gut barrier function and bile acid homeostasis in mice

Huikuan Chu, Lu Jiang, Bei Gao, Nagsen Gautam, Jawaher Abdullah Alamoudi, Sonja Lang, Yanhan Wang, Yi Duan, Yazen Alnouti, Edward E. Cable, Bernd Schnabl

2020Translational research31 citationsDOIOpen Access PDF

Topics & Concepts

Bile acidInternal medicineEndocrinologyPeroxisome proliferator-activated receptor deltaPeroxisome proliferator-activated receptorGut floraLiver functionLiquid dietAlcoholic liver diseaseHomeostasisChemistryEthanolBiologyBiochemistryReceptorMedicineNuclear receptorCirrhosisGeneTranscription factorLiver Disease Diagnosis and TreatmentPeroxisome Proliferator-Activated ReceptorsDiet and metabolism studies
The selective PPAR-delta agonist seladelpar reduces ethanol-induced liver disease by restoring gut barrier function and bile acid homeostasis in mice | Litcius