Chronic long‐COVID syndrome: A protracted COVID‐19 illness with neurological dysfunctions
Abdul Mannan Baig
Abstract
After almost a year of COVID-19, the chronic long-COVID syndrome has been recognized as an entity in 2021. The patients with the long-COVID are presenting with ominous neurological deficits that with time are becoming persistent and are causing disabilities in the affected individuals. The mechanisms underlying the neurological syndrome in long-COVID have remained obscure and need to be actively researched to find a resolution for the patients with long-COVID. Here, the factors like site of viral load, the differential immune response, neurodegenerative changes, and inflammation as possible causative factors are debated to understand and investigate the pathogenesis of neuro-COVID in long-COVID syndrome.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Medicine2019-20 coronavirus outbreakPathogenesisNeuroscienceImmunologyPsychologyVirologyDiseasePathologyOutbreakInfectious disease (medical specialty)Long-Term Effects of COVID-19Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders