Hydride transfer enabled switchable dearomatization of indoles in the carbocyclic ring and the pyrrole ring
Kang Duan, Hongjin Shi, Lin-Xuan Wang, Shuai‐Shuai Li, Lubin Xu, Jian Xiao
Abstract
Hydride transfer enabled the first success of the regioselective dearomatization of indoles in the carbocyclic ring and the pyrrole ring, which was induced by <italic>ortho</italic>-quinone methides and vinylogous iminium intermediates, respectively.
Topics & Concepts
ChemistryIminiumPyrroleRing (chemistry)RegioselectivityHydrideQuinoneMedicinal chemistryStereochemistryOrganic chemistryCatalysisMetalSynthesis of Indole DerivativesCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions