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LEFTY-PITX2 signaling pathway is critical for generation of mature and ventricular cardiac organoids in human pluripotent stem cell-derived cardiac mesoderm cells

Myeong-Hwa Song, Seung‐Cheol Choi, Ji-Min Noh, Hyung Joon Joo, Chi‐Yeon Park, Jung‐Joon Cha, Tae Hoon Ahn, Tae Hee Ko, Jong‐Il Choi, Ji Eun Na, Im Joo Rhyu, Yongjun Jang, Yongdoo Park, Jeong‐An Gim, Jong‐Hoon Kim, Do‐Sun Lim

2021Biomaterials19 citationsDOI

Topics & Concepts

Induced pluripotent stem cellCell biologyMesodermBiologyMyocyteSarcomereChemistryInternal medicineEmbryonic stem cellMedicineBiochemistryGeneTissue Engineering and Regenerative MedicinePluripotent Stem Cells ResearchCongenital heart defects research
LEFTY-PITX2 signaling pathway is critical for generation of mature and ventricular cardiac organoids in human pluripotent stem cell-derived cardiac mesoderm cells | Litcius