Total, renal and hepatic clearances of doxorubicin and formation clearance of doxorubicinol in patients with breast cancer: Estimation of doxorubicin hepatic extraction ratio
Leandro Francisco Pippa, Milena Locci de Oliveira, Adriana Rocha, Jurandyr Moreira de Andrade, Vera Lúcia Lanchote
Topics & Concepts
PharmacokineticsChemistryDoxorubicinPharmacologyBreast cancerPopulationMetaboliteCardiotoxicityVolume of distributionRenal functionUrologyChemotherapyCancerInternal medicineMedicineToxicityBiochemistryOrganic chemistryEnvironmental healthChemotherapy-induced cardiotoxicity and mitigationCancer Treatment and PharmacologyLung Cancer Research Studies