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Topoisomerase-modulated genome-wide DNA supercoiling domains colocalize with nuclear compartments and regulate human gene expression

Qian Yao, Linying Zhu, Zhen Shi, Subhadra Banerjee, Chongyi Chen

2024Nature Structural & Molecular Biology31 citationsDOI

Topics & Concepts

DNA supercoilTopoisomeraseBiologyChromatinDNAGeneGenomeTranscription (linguistics)Cell biologyMolecular biologyGeneticsDNA replicationPhilosophyLinguisticsGenomics and Chromatin DynamicsDNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniques
Topoisomerase-modulated genome-wide DNA supercoiling domains colocalize with nuclear compartments and regulate human gene expression | Litcius