The cyclimids: Degron-inspired cereblon binders for targeted protein degradation
Saki Ichikawa, N. Connor Payne, Wenqing Xu, Chia‐Fu Chang, Nandini Vallavoju, Spencer Frome, Hope A. Flaxman, Ralph Mazitschek, Christina M. Woo
Topics & Concepts
DegronCereblonChemistryTernary complexUbiquitin ligaseDegradation (telecommunications)BifunctionalTernary operationProtein degradationCell biologyComputational biologyUbiquitinBiochemistryBiologyComputer scienceEnzymeCatalysisTelecommunicationsGeneProgramming languageProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments