The MARCHF6 E3 ubiquitin ligase acts as an NADPH sensor for the regulation of ferroptosis
Kha The Nguyen, Sang-Hyeon Mun, Jihye Yang, Jongeun Lee, Ok-Hee Seok, Eunjeong Kim, Dasom Kim, So Young An, Dong-Young Seo, Jeong‐Yong Suh, Yoontae Lee, Cheol‐Sang Hwang
Topics & Concepts
Ubiquitin ligaseCell biologyUbiquitinEndoplasmic reticulumGPX4DNA ligaseChemistryTransmembrane proteinRegulatorBiologyBiochemistryOxidative stressCatalaseEnzymeGeneReceptorGlutathione peroxidaseFerroptosis and cancer prognosisRNA modifications and cancerCancer, Lipids, and Metabolism