Imp7 siRNA nanoparticles protect against mechanical ventilation-associated liver injury by inhibiting HMGB1 production and NETs formation

Ning Ding, Hui Xiao, Lixiao Zhen, Huiqing Li, Zengzhen Zhang, Junke Ge

2024Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease14 citationsDOI

Topics & Concepts

HMGB1TLR4Liver injuryNeutrophil extracellular trapsChemistryMechanical ventilationInflammationMediatorPharmacologyProinflammatory cytokineSecretionMedicineImmunologyBiochemistryAnesthesiaInternal medicineNeutrophil, Myeloperoxidase and Oxidative MechanismsAdvanced Glycation End Products researchImmune Response and Inflammation