Integrated analysis of public datasets for the discovery and validation of survival-associated genes in solid tumors
Balázs Győrffy
Abstract
(HR = 2.65). In summary, a new integrated database for colon cancer is presented. A colon cancer analysis subsystem was integrated into our Kaplan-Meier plotter that can be used to mine the entire database (https://www.kmplot.com). The portal has the potential to be employed for the identification and prioritization of promising biomarkers and therapeutic target candidates in multiple solid tumors including, among others, breast, lung, ovarian, gastric, pancreatic, and colon cancers.
Topics & Concepts
Colorectal cancerSurvival analysisProportional hazards modelGeneTranscriptomeCancerMultivariate analysisComputational biologyFalse discovery rateOncologyMedicineBiologyBioinformaticsGene expressionInternal medicineGeneticsColorectal Cancer Treatments and StudiesGenetic factors in colorectal cancerCancer, Lipids, and Metabolism