Review of the new APLS guideline (2022): Management of the convulsing child
Melody Bacon, Richard Appleton, Harish Bangalore, Celia Brand, Juliet Browning, Richard Chin, Satvinder Mahal, Susana Saranga Estevan, Kirsten McHale, Ailsa McLellan, Nicola Milne, Suresh Pujar, T Hemanth Rao, Steven A. Short, Stephen Warriner, Michael Yoong
Abstract
Convulsive status epilepticus (CSE) (box 1) is the most common childhood medical neurological emergency, with an incidence of approximately 20 per 100000 per year in the developed world.1 2 CSE can be fatal, but mortality is lower in children than in adults—at about 2%–7%.3 Adverse neurological consequences following CSE consist of subsequent epilepsy, motor deficits, and learning and behavioural difficulties. The main determinant of outcome is the underlying aetiology (box 2). There is low risk of morbidity and mortality in children with unprovoked/prolonged febrile CSE. This risk increases significantly in cases with structural or genetic causes. https://ep.bmj.com/content/108/1/43 This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. http://creativecommons.org/licenses/by-nc/4.0/ DOI http://dx.doi.org/10.1136/archdischild-2021-323351