Design, synthesis, kinetic, molecular dynamics, and hypoglycemic effect characterization of new and potential selective benzimidazole derivatives as Protein Tyrosine Phosphatase 1B inhibitors
Mara Ibeth Campos-Almazán, Miguel Flores-Ramos, Alicia Hernández‐Campos, Rafael Castillo, Erick Sierra‐Campos, Kristiane R. Torgeson, Wolfgang Peti, Mónica Valdez‐Solana, Jesús Oria‐Hernández, Sara T. Méndez, Adriana Castillo‐Villanueva, Hugo Jiménez-de Jesús, Claudia Avitia‐Domínguez, Alfredo Téllez‐Valencia
Topics & Concepts
BenzimidazoleChemistryProtein tyrosine phosphataseLinkerStereochemistryEnzymeBiochemistryComputer scienceOperating systemOrganic chemistryProtein Tyrosine PhosphatasesGalectins and Cancer BiologyBioactive Compounds and Antitumor Agents