A G-quadruplex nanoswitch in the SGK1 promoter regulates isoform expression by K+/Na+ balance and resveratrol binding
Mengjie Chen, Qi Chen, Yirui Li, Zhenjun Yang, Ethan Will Taylor, Lijun Zhao
Topics & Concepts
SGK1Epithelial sodium channelChemistryResveratrolGene isoformPromoterTranscription factorTranscription (linguistics)SodiumPotassiumSodium channelWestern blotMolecular biologyGene expressionBiochemistryCell biologyKinaseGeneBiologyOrganic chemistryLinguisticsPhilosophyIon Transport and Channel RegulationRenin-Angiotensin System StudiesDNA and Nucleic Acid Chemistry