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Dynamics of Population Immunity Due to the Herd Effect in the COVID-19 Pandemic

Vicente Javier Clemente‐Suárez, Alberto J. Hormeño-Holgado, Manuel Jiménez, Juan Camilo Benítez-Agudelo, Eduardo Navarro-Jiménez, Natalia Perez-Palencia, Ronald Maestre–Serrano, Carmen Cecilia Laborde-Cárdenas, José Francisco Tornero-Aguilera

2020Vaccines127 citationsDOIOpen Access PDF

Abstract

The novel Coronavirus 2 Severe Acute Respiratory Syndrome (SARS-Cov-2) has led to the Coronavirus Disease 2019 (COVID-19) pandemic, which has surprised health authorities around the world, quickly producing a global health crisis. Different actions to cope with this situation are being developed, including confinement, different treatments to improve symptoms, and the creation of the first vaccines. In epidemiology, herd immunity is presented as an area that could also solve this new global threat. In this review, we present the basis of herd immunology, the dynamics of infection transmission that induces specific immunity, and how the application of immunoepidemiology and herd immunology could be used to control the actual COVID-19 pandemic, along with a discussion of its effectiveness, limitations, and applications.

Topics & Concepts

PandemicHerd immunityCoronavirus disease 2019 (COVID-19)CoronavirusImmunityTransmission (telecommunications)PopulationEpidemiologyImmunologyGlobal healthSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)DiseaseVirologyPublic healthMedicineEnvironmental healthInfectious disease (medical specialty)Immune systemComputer scienceTelecommunicationsPathologyInternal medicineNursingSARS-CoV-2 and COVID-19 ResearchCOVID-19 epidemiological studiesViral Infections and Outbreaks Research
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