NLRP10 promotes AGEs-induced NLRP1 and NLRP3 inflammasome activation via ROS/MAPK/NF-κB signaling in human periodontal ligament cells
Xiaowei Yi, Yao Song, Jialei Xu, Liu Wang, Liu Liu, Dingming Huang, Lan Zhang
Topics & Concepts
InflammasomeMAPK/ERK pathwayInflammationCell biologyChemistryPeriodontal fiberGlycationNF-κBSignal transductionProinflammatory cytokineReactive oxygen speciesOxidative stressReceptorCancer researchImmunologyMedicineBiologyBiochemistryDentistryAdvanced Glycation End Products researchHeme Oxygenase-1 and Carbon MonoxideInflammasome and immune disorders