Direct Synthesis of Propen-2-yl Sulfones through Cascade Reactions Using Calcium Carbide as an Alkyne Source
Lei Gao, Zhenrong Liu, Xiaolong Ma, Zheng Li
Abstract
A simple method for the construction of propen-2-yl sulfones through cascade reactions of calcium carbide with arylsulfonylhydrazones using copper as a mediator is described. The salient features of this protocol are the use of readily available and easy-to-handle alkyne source, broad substrate scope, open-air condition, and simple operation procedure.
Topics & Concepts
ChemistryAlkyneCascadeSubstrate (aquarium)Calcium carbideCombinatorial chemistryScope (computer science)CatalysisOrganic chemistryChromatographyComputer scienceProgramming languageGeologyOceanographyCyclopropane Reaction MechanismsSulfur-Based Synthesis TechniquesCatalytic Alkyne Reactions