Probing the biological activity of isatin derivatives against human lung cancer A549 cells: Cytotoxicity, CT-DNA/BSA binding, DFT/TD-DFT, topology, ADME-Tox, docking and dynamic simulations
Mehran Feizi‐Dehnayebi, Ghodsi Mohammadi Ziarani, T.N. Lohith, Somayyeh Ghareghomi, Zahra Panahande, Majid Farsadrooh, Maryam Majidinia
Topics & Concepts
IsatinADMECytotoxicityA549 cellChemistryDNAComputational chemistryTopology (electrical circuits)Combinatorial chemistryBiochemistryOrganic chemistryCellIn vitroMathematicsCombinatoricsComputational Drug Discovery MethodsSynthesis and biological activityCancer therapeutics and mechanisms