Towards the enzymatic synthesis of phosphorothioate containing LNA oligonucleotides
Marie Flamme, Steven P. Hanlon, Hans Iding, Kurt Puentener, Filippo Sladojevich, Marcel Hollenstein
Topics & Concepts
ChemistryOligonucleotideThio-Chemical synthesisCombinatorial chemistryEnzymePhosphoramidateThiophosphateChemical modificationNucleotideStereochemistryNucleosideDeoxyribozymeBiochemistryDNAIn vitroOrganic chemistryGeneAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryRNA Interference and Gene Delivery