Impact of cross-ancestry genetic architecture on GWASs in admixed populations
Rachel Mester, Kangcheng Hou, Yi Ding, Gillian Meeks, Kathryn S. Burch, Arjun Bhattacharya, Brenna M. Henn, Bogdan Paşaniuc
Topics & Concepts
BiologyGenome-wide association studyGenetic associationPopulation stratificationAncestry-informative markerEvolutionary biologyGenetic architecturePopulationGeneticsAlleleLinkage disequilibrium1000 Genomes ProjectSingle-nucleotide polymorphismGenetic admixtureGenetic genealogyAllele frequencyGenotypeQuantitative trait locusHaplotypeDemographyGeneSociologyGenetic Associations and EpidemiologyGenetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and Animals