Soybean lectin-triggered IL-6 secretion induces autophagy to kill intracellular mycobacteria through P2RX7 dependent activation of the JAK2/STAT3/Mcl-1 pathway
Abtar Mishra, Ashish Kumar, Lincoln Naik, Salina Patel, Mousumi Das, Assirbad Behura, Dev Kiran Nayak, Amit Mishra, Sujit K. Bhutia, Ramandeep Singh, Rohan Dhiman
Topics & Concepts
AutophagyPI3K/AKT/mTOR pathwayCell biologyAutocrine signallingSTAT3SecretionCytokineProtein kinase BSignal transductionMAPK/ERK pathwayIntracellularBiologyChemistryReceptorImmunologyApoptosisBiochemistryMycobacterium research and diagnosisAutophagy in Disease and TherapyImmune Cell Function and Interaction