Biomimetic triphasic silk fibroin scaffolds seeded with tendon-derived stem cells for tendon-bone junction regeneration
Yiyun Geng, Penglei Cui, Muli Hu, Bingjun Zhang, Liming Dai, Fengxuan Han, Yungshu-hang Patrick, Sai‐Chuen Fu, Bin Li, Xiaoling Zhang
Abstract
studies of the rTDSC-seeded scaffold in a rat TBJ rupture model showed tendon tissue regeneration with a clear transition zone within 8 weeks of implantation. These results indicated that the biomimetic triphasic SF scaffolds seeded with rTDSCs have great potential to be applied in TBJ regeneration.
Topics & Concepts
FibroinRegeneration (biology)TendonSILKStem cellChemistryAnatomyBiomedical engineeringMaterials scienceCell biologyBiologyComposite materialMedicineSilk-based biomaterials and applicationsTendon Structure and TreatmentKnee injuries and reconstruction techniques