An acceptor-shielding strategy of photosensitizers for enhancing the generation efficiency of type I reactive oxygen species and the related photodynamic immunotherapy
Jiamin Qu, Yahui Zhang, Zhengxu Cai, Bin Tong, Hai‐Yan Xie, Yuping Dong, Jianbing Shi
Abstract
The “acceptor-shielding” strategy is adopted, that is, two dodecyls of the multiarylpyrroles are introduced into the acceptor that can enhance the production of pure type I ROS, for realizing the synergistic effect of PDT and immunotherapy.
Topics & Concepts
Photodynamic therapyReactive oxygen speciesElectromagnetic shieldingAcceptorOxygenPhotochemistryMaterials scienceNanotechnologyCombinatorial chemistryChemistryOrganic chemistryBiochemistryComposite materialPhysicsCondensed matter physicsNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesLuminescence and Fluorescent Materials