A novel lurasidone hydrochloride–shikimic acid co-amorphous system formed by hydrogen-bonding interaction with the retained pH-dependent solubility behavior
Yi Hu, Cuiping Jiang, Bin Li, Lijing Zhou, Renjie Xu, Yüjie Guo, Yan Cao, Guosheng Cao, Shan Lu
Abstract
The current study was aimed at investigating the lurasidone hydrochloride–shikimic acid co-amorphous system using a new type of organic acid.
Topics & Concepts
Shikimic acidChemistrySolubilityHydrochlorideAmorphous solidLurasidoneHydrogen bondOrganic chemistryNuclear chemistryInorganic chemistryMoleculeAntipsychoticSchizophrenia (object-oriented programming)Computer scienceProgramming languageAnalytical Chemistry and ChromatographySurfactants and Colloidal SystemsThermal and Kinetic Analysis