Novel trajectories of the NK1R antagonist aprepitant in rotenone-induced Parkinsonism-like symptoms in rats: Involvement of ERK5/KLF4/p62/Nrf2 signaling axis
Asmaa M. El-Deeb, Ahmed F. Mohamed, Mohammed F. EL-Yamany, Dalia M. El-Tanbouly
Topics & Concepts
RotenoneNeurotoxicityNeuroprotectionAutophagyPharmacologySignal transductionChemistryCell biologyKLF4BiologyInternal medicineMedicineBiochemistryTranscription factorToxicitySOX2GeneApoptosisMitochondrionParkinson's Disease Mechanisms and TreatmentsKruppel-like factors researchGenomics, phytochemicals, and oxidative stress