Dual silencing of tumor-intrinsic VISTA and CTLA-4 stimulates T-cell mediated immune responses and inhibits MCF7 breast cancer development
Negar Hosseinkhani, Nima Hemmat, Elham Baghbani, Amir Baghbanzadeh, Tohid Kazemi, Ahad Mokhtarzadeh, Mahdi Jafarlou, Mohammad Amin Doustvandi, Behzad Baradaran
Topics & Concepts
BiologyCTLA-4Cytotoxic T cellGene knockdownCancer researchImmune systemGene silencingT cellApoptosisImmunologyIn vitroBiochemistryGeneCancer Immunotherapy and BiomarkersImmune cells in cancerT-cell and B-cell Immunology